Hiroshi Kido Selected Research

pyruvate dehydrogenase kinase 4

10/2019	Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer.
9/2016	Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
1/2014	Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.

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Hiroshi Kido Research Topics

Disease

38	Human Influenza (Influenza) 01/2021 - 02/2003
27	Infections 12/2021 - 05/2002
10	Brain Diseases (Brain Disorder) 09/2016 - 06/2004
7	Virus Diseases (Viral Diseases) 12/2021 - 05/2002
6	Multiple Organ Failure (MODS) 11/2019 - 11/2008
6	Fever (Fevers) 01/2019 - 10/2006
6	Inflammation (Inflammations) 02/2018 - 06/2007
4	Food Hypersensitivity (Food Allergy) 01/2019 - 02/2013
4	Brain Edema (Cerebral Edema) 01/2012 - 07/2003
4	Influenza in Birds (Avian Flu) 01/2012 - 05/2002
3	Prion Diseases (Transmissible Spongiform Encephalopathies) 12/2021 - 01/2018
3	Egg Hypersensitivity (Egg Allergy) 07/2020 - 01/2016
3	Cytokine Release Syndrome 11/2019 - 01/2014
3	Neoplasms (Cancer) 10/2019 - 12/2003
2	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2020 - 07/2006
2	Eczema 01/2019 - 01/2017
2	Heat Stroke (Heatstroke) 01/2019 - 01/2016
2	Milk Hypersensitivity (Milk Allergy) 08/2018 - 12/2017
2	Myocarditis (Carditis) 09/2014 - 02/2011
2	Reinfection 01/2013 - 11/2012
2	Reye Syndrome (Reye's Syndrome) 01/2012 - 06/2004
2	Encephalitis (Encephalitis, Rasmussen) 04/2006 - 02/2003
1	Acute Disease 02/2022
1	Neuroblastoma 12/2021
1	Scrapie 01/2020
1	Bovine Spongiform Encephalopathy (Mad Cow Disease) 01/2020
1	Pancreatic Neoplasms (Pancreatic Cancer) 10/2019
1	Disseminated Intravascular Coagulation 01/2019

Drug/Important Bio-Agent (IBA)

18	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 05/2002
16	TrypsinIBA 11/2019 - 05/2002
11	CytokinesIBA 11/2019 - 02/2003
10	Immunoglobulin A (IgA)IBA 01/2019 - 08/2001
10	Hemagglutinins (Hemagglutinin)IBA 01/2019 - 02/2003
8	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 01/2019 - 10/2006
8	Immunoglobulin G (IgG)IBA 01/2019 - 09/2006
8	Neuraminidase (Sialidase)IBA 09/2016 - 11/2004
7	Adenosine Triphosphate (ATP)IBA 02/2022 - 10/2006
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2002
6	Antiviral Agents (Antivirals)IBA 01/2021 - 11/2009
6	Immunoglobulin E (IgE)IBA 07/2020 - 02/2013
6	Secretory Immunoglobulin A (SIgA)IBA 01/2019 - 10/2008
6	AntigensIBA 11/2013 - 05/2003
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2007
5	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2019 - 11/2004
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 07/2003
5	Clarithromycin (Biaxin)FDA LinkGeneric 02/2018 - 01/2007
5	Glycoproteins (Glycoprotein)IBA 02/2011 - 05/2002
4	Protein Isoforms (Isoforms)IBA 12/2021 - 07/2006
4	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 01/2014
4	VaccinesIBA 01/2019 - 01/2006
4	Oseltamivir (Tamiflu)FDA Link 10/2012 - 11/2009
4	Fibrinolysin FDA Link 10/2006 - 02/2003
3	Prion ProteinsIBA 12/2021 - 01/2018
3	Protease Inhibitors (Protease Inhibitor)IBA 11/2019 - 05/2003
3	pyruvate dehydrogenase kinase 4IBA 10/2019 - 01/2014
3	AllergensIBA 01/2019 - 01/2016
3	Interleukin-6 (Interleukin 6)IBA 02/2018 - 10/2010
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 02/2018 - 02/2010
3	AntibodiesIBA 01/2018 - 09/2006
3	EnzymesIBA 01/2018 - 05/2002
3	Carnitine (L-Carnitine)FDA LinkGeneric 09/2016 - 12/2007
3	BezafibrateIBA 09/2016 - 11/2011
3	MacrolidesIBA 10/2012 - 01/2007
3	Matrix Metalloproteinases (MMPs)IBA 02/2011 - 02/2010
3	acylcarnitineIBA 05/2008 - 10/2006
2	Lactic Acid (Lactate)FDA LinkGeneric 02/2022 - 01/2013
2	Monoclonal AntibodiesIBA 01/2020 - 09/2006
2	Serine Proteases (Serine Protease)IBA 11/2019 - 05/2010
2	Cholera ToxinIBA 01/2019 - 10/2008
2	Omalizumab (Xolair)FDA Link 08/2018 - 12/2017
2	TrypsinogenIBA 01/2018 - 06/2008
2	OvomucinIBA 01/2017 - 01/2016
2	diisopropylamine dichloroacetate (DIPA)IBA 09/2016 - 01/2014
2	Carnitine palmitoyl transferase 2 deficiencyIBA 01/2016 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 01/2013
2	Trypsin InhibitorsIBA 09/2014 - 02/2011
2	Aprotinin (Trasylol)FDA Link 09/2014 - 02/2011
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2012 - 01/2007
2	FurinIBA 01/2012 - 05/2010
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2012 - 06/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2010 - 02/2010
2	Messenger RNA (mRNA)IBA 12/2007 - 12/2003
2	Ambroxol (Mucosolvan)IBA 01/2007 - 11/2004
2	AntioxidantsIBA 01/2007 - 11/2004
2	Expectorants (Mucolytics)IBA 01/2007 - 11/2004
2	Secretory Leukocyte Peptidase InhibitorIBA 11/2004 - 05/2003
1	Protein AggregatesIBA 12/2021
1	PrionsIBA 12/2021
1	src-Family KinasesIBA 01/2020
1	Dasatinib (BMS 354825)FDA Link 01/2020
1	AgarIBA 10/2019
1	cryptotanshinoneIBA 10/2019
1	Dacarbazine (DIC)FDA LinkGeneric 01/2019
1	Immunoglobulin IsotypesIBA 01/2019
1	AntithrombinsIBA 01/2019
1	ChemokinesIBA 02/2018

Therapy/Procedure

3	Therapeutics 10/2019 - 01/2007
3	Immunotherapy 08/2018 - 01/2016
2	Intranasal Administration 10/2008 - 01/2006
1	Aftercare (After-Treatment) 01/2020